Mouse Ggh activation kit by CRISPRa

CAT#: GA201599

Ggh CRISPRa kit - CRISPR gene activation of mouse gamma-glutamyl hydrolase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ggh
• Locus ID: 14590
• Kit Components:

  GA201599G1, Ggh gRNA vector 1 in pCas-Guide-CRISPRa

  GA201599G2, Ggh gRNA vector 2 in pCas-Guide-CRISPRa

  GA201599G3, Ggh gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010281
• Synonyms: gamma-GH
• Summary: Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. Acts as endopeptidase. Lysosomal enzyme is activated by sulfhydryl compounds. [UniProtKB/Swiss-Prot Function]