Mouse Gnai2 activation kit by CRISPRa

CAT#: GA201649

Gnai2 CRISPRa kit - CRISPR gene activation of mouse guanine nucleotide binding protein (G protein), alpha inhibiting 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Gnai2
• Locus ID: 14678
• Kit Components:

  GA201649G1, Gnai2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201649G2, Gnai2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201649G3, Gnai2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008138
• Synonyms: C76432; Galphai2; Gia; Gnai-2
• Summary: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. [UniProtKB/Swiss-Prot Function]