Mouse Grm8 activation kit by CRISPRa

CAT#: GA201747

Grm8 CRISPRa kit - CRISPR gene activation of mouse glutamate receptor, metabotropic 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Grm8
• Locus ID: 14823
• Kit Components:

  GA201747G1, Grm8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201747G2, Grm8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201747G3, Grm8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001311072, NM_008174, NM_001361125
• Synonyms: A230002O04; Gprc1h; mGluR8
• Summary: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. [UniProtKB/Swiss-Prot Function]