Mouse Guca1a activation kit by CRISPRa

CAT#: GA201782

Guca1a CRISPRa kit - CRISPR gene activation of mouse guanylate cyclase activator 1a (retina)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Guca1a
• Locus ID: 14913
• Kit Components:

  GA201782G1, Guca1a gRNA vector 1 in pCas-Guide-CRISPRa

  GA201782G2, Guca1a gRNA vector 2 in pCas-Guide-CRISPRa

  GA201782G3, Guca1a gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008189
• Synonyms: GC-A; Gcap1; Guca1; mGCAP1
• Summary: This gene encodes a calcium-binding photoreceptor protein. The encoded protein may be involved in modulation of guanylyl cyclase activity, and in turn, the mammalian cone phototransduction cascade. Disruption of this gene results in the retinal degeneration associated with cone dystrophy. [provided by RefSeq, Dec 2015]