Mouse Hsf2 activation kit by CRISPRa

CAT#: GA202011

Hsf2 CRISPRa kit - CRISPR gene activation of mouse heat shock factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Hsf2
• Locus ID: 15500
• Kit Components:

  GA202011G1, Hsf2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202011G2, Hsf2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202011G3, Hsf2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008297
• Synonyms: AI661205
• Summary: DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. HSF2 is expressed in a form that binds DNA constitutively but loses DNA binding by incubation at greater than 41 degrees C. [UniProtKB/Swiss-Prot Function]