Mouse Kcnh3 activation kit by CRISPRa

CAT#: GA202262

Kcnh3 CRISPRa kit - CRISPR gene activation of mouse potassium voltage-gated channel, subfamily H (eag-related), member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Kcnh3
• Locus ID: 16512
• Kit Components:

  GA202262G1, Kcnh3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202262G2, Kcnh3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202262G3, Kcnh3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010601
• Synonyms: AU019351; C030044P22Rik; Elk2; Kv12.2; Melk2
• Summary: The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. An increase in cognitive function was observed when this gene was knocked out, while deletion of the gene resulted in hippocampal hyperexcitability and epilepsy. [provided by RefSeq, Sep 2015]