Mouse Ldha activation kit by CRISPRa

CAT#: GA202431

Ldha CRISPRa kit - CRISPR gene activation of mouse lactate dehydrogenase A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ldha
• Locus ID: 16828
• Kit Components:

  GA202431G1, Ldha gRNA vector 1 in pCas-Guide-CRISPRa

  GA202431G2, Ldha gRNA vector 2 in pCas-Guide-CRISPRa

  GA202431G3, Ldha gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136069, NM_010699, NR_102727
• Synonyms: l7R2; Ldh1; Ldhm
• Summary: The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to hemolytic anemia and early postimplantation death in mice. Multiple transcript variants encoding different isoforms have been found for this gene. The mouse genome contains multiple pseudogenes of this gene. [provided by RefSeq, May 2013]