Mouse Mknk1 activation kit by CRISPRa

CAT#: GA202664

Mknk1 CRISPRa kit - CRISPR gene activation of mouse MAP kinase-interacting serine/threonine kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Mknk1
• Locus ID: 17346
• Kit Components:

  GA202664G1, Mknk1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202664G2, Mknk1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202664G3, Mknk1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001285487, NM_001285488, NM_021461, NM_001355174, NM_001369238
• Synonyms: 2410048M24Rik; Mnk1
• Summary: This gene encodes a serine-threonine protein kinase that is activated by extracellular signal-regulated kinase or p38 mitogen-activated protein kinases, and it may function in cytokine and environmental stress responses. This kinase is required for phosphorylation of eukaryotic translation initiation factor 4E but it is not required for cell growth during development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Oct 2013]