Mouse Myo10 activation kit by CRISPRa
CAT#: GA202801
Myo10 CRISPRa kit - CRISPR gene activation of mouse myosin X
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Myo10 |
Locus ID | 17909 |
Kit Components | GA202801G1, Myo10 gRNA vector 1 in pCas-Guide-CRISPRa GA202801G2, Myo10 gRNA vector 2 in pCas-Guide-CRISPRa GA202801G3, Myo10 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_019472, NM_001353141, NM_001353142 |
Synonyms | AW048724; D15Ertd600e; mKIAA0799; myosin-X |
Summary | Isoform Headless: Functions as a dominant-negative regulator of isoform 1, suppressing its filopodia-inducing and axon outgrowth-promoting activities. In hippocampal neurons, it increases VASP retention in spine heads to induce spine formation and spine head expansion. [UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN510621 | Myo10 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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