Mouse Nos2 activation kit by CRISPRa

CAT#: GA202934

Nos2 CRISPRa kit - CRISPR gene activation of mouse nitric oxide synthase 2, inducible

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Nos2
• Locus ID: 18126
• Kit Components:

  GA202934G1, Nos2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202934G2, Nos2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202934G3, Nos2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313921, NM_001313922, NM_010927
• Synonyms: i-NOS; iNOS; MAC-NOS; Nos-2; NOS-II; Nos2a
• Summary: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase that is inducible by a combination of lipopolysaccharide and certain cytokines. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]