Mouse Npr1 activation kit by CRISPRa

CAT#: GA202952

Npr1 CRISPRa kit - CRISPR gene activation of mouse natriuretic peptide receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Npr1
• Locus ID: 18160
• Kit Components:

  GA202952G1, Npr1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202952G2, Npr1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202952G3, Npr1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008727
• Synonyms: AI893888; GC-A; NPR-A; NPRA; Pndr
• Summary: Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. [UniProtKB/Swiss-Prot Function]