Mouse Cxcl12 activation kit by CRISPRa

CAT#: GA203814

Cxcl12 CRISPRa kit - CRISPR gene activation of mouse chemokine (C-X-C motif) ligand 12

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cxcl12
• Locus ID: 20315
• Kit Components:

  GA203814G1, Cxcl12 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203814G2, Cxcl12 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203814G3, Cxcl12 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012477, NM_013655, NM_021704
• Synonyms: Pbsf; Scyb12; Sdf1; Tlsf; Tpar1
• Summary: This gene encodes a member of the alpha chemokine protein family. The encoded protein is secreted and functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4. The encoded protein plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]