Mouse Sema3b activation kit by CRISPRa

CAT#: GA203832

Sema3b CRISPRa kit - CRISPR gene activation of mouse sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sema3b
• Locus ID: 20347
• Kit Components:

  GA203832G1, Sema3b gRNA vector 1 in pCas-Guide-CRISPRa

  GA203832G2, Sema3b gRNA vector 2 in pCas-Guide-CRISPRa

  GA203832G3, Sema3b gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042779, NM_001291537, NM_001291538, NM_001291539, NM_009153, NR_111986
• Synonyms: SemA; sema5; Semaa; semaV
• Summary: This gene encodes a secreted protein that belongs to the class 3 semaphorin/collapsin family. Members of this family play a role in growth cone guidance during neurogenesis. The encoded protein inhibits axonal extension. This protein is thought to be an osteoblast protein that regulates bone mass and affects skeletal homeostasis. A similar gene in humans functions as a tumor suppressor gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]