Mouse St6galnac4 activation kit by CRISPRa

CAT#: GA203897

St6galnac4 CRISPRa kit - CRISPR gene activation of mouse ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: St6galnac4
• Locus ID: 20448
• Kit Components:

  GA203897G1, St6galnac4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203897G2, St6galnac4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203897G3, St6galnac4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001276425, NM_011373
• Synonyms: SIAT7-D; Siat7d; ST6GalNAcIV
• Summary: Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. Prefers glycoproteins to glycolipids. [UniProtKB/Swiss-Prot Function]