Mouse Sumo3 activation kit by CRISPRa

CAT#: GA203995

Sumo3 CRISPRa kit - CRISPR gene activation of mouse small ubiquitin-like modifier 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sumo3
• Locus ID: 20610
• Kit Components:

  GA203995G1, Sumo3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203995G2, Sumo3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203995G3, Sumo3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301671, NM_001301672, NM_001301673, NM_019929, NR_125903, NR_125904
• Synonyms: 2810014B19Rik; D10Ertd345e; SMT3A; Smt3h1; SUMO-3
• Summary: This gene encodes a member of the small ubiquitin-like modifier family. The encoded protein may regulate a variety of proteins in many pathways via a post-translational modification, known as SUMOylation. This activity may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Disruption of some of these processes has been associated with cerebral ischemia, neural dysfunction, and heart disease. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]