Mouse Tkt activation kit by CRISPRa

CAT#: GA204362

Tkt CRISPRa kit - CRISPR gene activation of mouse transketolase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Tkt
• Locus ID: 21881
• Kit Components:

  GA204362G1, Tkt gRNA vector 1 in pCas-Guide-CRISPRa

  GA204362G2, Tkt gRNA vector 2 in pCas-Guide-CRISPRa

  GA204362G3, Tkt gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009388
• Synonyms: p68
• Summary: This gene encodes an enzyme that binds magnesium and thiamine pyrophosphate and catalyzes the transfer of sugar phosphates to an aldose acceptor. This enzyme is a key component of the pentose phosphate pathway during glycolysis. It is significantly expressed in the cornea and may be involved in the cellular response against oxidative stress. Haploinsufficiency of this gene leads to decreased growth and reduction of adipose tissue. [provided by RefSeq, Dec 2013]