Mouse Tpo activation kit by CRISPRa
CAT#: GA204427
Tpo CRISPRa kit - CRISPR gene activation of mouse thyroid peroxidase
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Tpo |
Locus ID | 22018 |
Kit Components | GA204427G1, Tpo gRNA vector 1 in pCas-Guide-CRISPRa GA204427G2, Tpo gRNA vector 2 in pCas-Guide-CRISPRa GA204427G3, Tpo gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_009417 |
Summary | This gene encodes a membrane-bound glycoprotein. The encoded enzyme plays a central role in thyroid gland function. The enzyme functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mice with homozygous missense mutations in this gene exhibit hypothyroid dwarfism and hearing impairment. [provided by RefSeq, Sep 2015] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN518096 | Tpo - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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