Mouse Unc119 activation kit by CRISPRa

CAT#: GA204543

Unc119 CRISPRa kit - CRISPR gene activation of mouse unc-119 lipid binding chaperone


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Unc119
Locus ID 22248
Kit Components

GA204543G1, Unc119 gRNA vector 1 in pCas-Guide-CRISPRa

GA204543G2, Unc119 gRNA vector 2 in pCas-Guide-CRISPRa

GA204543G3, Unc119 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001313985, NM_001313986, NM_001313987, NM_001313988, NM_011676
Synonyms D11Bhm52; HRG4; MRG4; Rg4; Rtg4; Unc119h
Summary The protein encoded by this gene is multifunctional, affecting trafficking of transducin in rod photoreceptors, interacting with src-type tyrosine kinases through SH2 and SH3 interacting domains, and aiding the uptake of bacteria through endocytosis. In addition, the encoded protein acts as a lipid-binding chaperone to help localize some myristoylated proteins correctly. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.