Mouse Zp2 activation kit by CRISPRa

CAT#: GA204750

Zp2 CRISPRa kit - CRISPR gene activation of mouse zona pellucida glycoprotein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Zp2
• Locus ID: 22787
• Kit Components:

  GA204750G1, Zp2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204750G2, Zp2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204750G3, Zp2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_011775
• Synonyms: Zp-2
• Summary: This gene encodes a member of the zona pellucida family of glycoproteins that play an important role in the survival of growing oocytes, successful fertilization and the passage of early embryos through the oviduct. The encoded preproprotein undergoes proteolytic processing to generate the mature polypeptide that is incorporated into the extracellular matrix surrounding mouse oocytes. Mice lacking the encoded protein develop defective zonae pellucidae that disrupt folliculogenesis, fertility and development. [provided by RefSeq, Sep 2016]