Mouse Adam23 activation kit by CRISPRa

CAT#: GA204755

Adam23 CRISPRa kit - CRISPR gene activation of mouse a disintegrin and metallopeptidase domain 23

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Adam23
• Locus ID: 23792
• Kit Components:

  GA204755G1, Adam23 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204755G2, Adam23 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204755G3, Adam23 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177600, NM_011780
• Synonyms: AW046396; MDC3
• Summary: This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an inactive metalloprotease and disintegrin domains. Transgenic disruption of this gene in mice results in postnatal neurological defects including tremor and ataxia resulting in death by 2 weeks of age. [provided by RefSeq, Sep 2015]