Mouse Gria3 activation kit by CRISPRa

CAT#: GA205594

Gria3 CRISPRa kit - CRISPR gene activation of mouse glutamate receptor, ionotropic, AMPA3 (alpha 3)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Gria3
• Locus ID: 53623
• Kit Components:

  GA205594G1, Gria3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA205594G2, Gria3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA205594G3, Gria3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281929, NM_001290451, NM_016886, NR_104053, NM_001358361
• Synonyms: 2900064I19Rik; GluA3; Glur-3; GluR-C; GluR-K3; Glur3; Gluralpha3
• Summary: This gene encodes a multi-pass transmembrane protein that forms a homotetramer or heterotetramer in neuronal cells. The encoded protein is a ligand-gated ion channel that responds to the neurotransmitter L-glutamate to promote synaptic transmission. Deficiency of this gene leads to behavioral phenotypes. The transcript is subject to RNA editing at codon 769 (AGA->GGA; R->G). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]