Mouse Chst11 activation kit by CRISPRa

CAT#: GA206291

Chst11 CRISPRa kit - CRISPR gene activation of mouse carbohydrate sulfotransferase 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Chst11
• Locus ID: 58250
• Kit Components:

  GA206291G1, Chst11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA206291G2, Chst11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA206291G3, Chst11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021439
• Synonyms: 1110020P09Rik; C4s; C4ST; C4ST-1; C4ST1
• Summary: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor. [UniProtKB/Swiss-Prot Function]