Mouse Sbds activation kit by CRISPRa

CAT#: GA206917

Sbds CRISPRa kit - CRISPR gene activation of mouse SBDS ribosome maturation factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sbds
• Locus ID: 66711
• Kit Components:

  GA206917G1, Sbds gRNA vector 1 in pCas-Guide-CRISPRa

  GA206917G2, Sbds gRNA vector 2 in pCas-Guide-CRISPRa

  GA206917G3, Sbds gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_023248
• Synonyms: 4733401P19Rik; AI836084; CGI-97; SDS
• Summary: This gene encodes a protein that is necessary for ribosome function and maintaining normal levels of protein synthesis. The encoded protein may function to activate ribosomes for translation, and may be involved in cellular response to stress and DNA damage. Loss of this gene is embryonic lethal while deficiency of the encoded protein in the pancreas is associated with symptoms of Shwachman-Diamond syndrome. [provided by RefSeq, Dec 2015]