Mouse Taz activation kit by CRISPRa

CAT#: GA206976

Taz CRISPRa kit - CRISPR gene activation of mouse tafazzin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Taz
• Locus ID: 66826
• Kit Components:

  GA206976G1, Taz gRNA vector 1 in pCas-Guide-CRISPRa

  GA206976G2, Taz gRNA vector 2 in pCas-Guide-CRISPRa

  GA206976G3, Taz gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001173547, NM_001242615, NM_001242616, NM_001290738, NM_181516, NR_033394, NR_033395
• Synonyms: 5031411C02Rik; 9130012G04Rik; AW107266; AW552613; G4.5
• Summary: This gene encodes a mitochondrial phospholipid-lysophospholipid transacylase necessary for normal composition and content of cardiolipin. In humans, mutations of this gene result in Barth syndrome, most often characterized by cardioskeletal myopathy, neutropenia and abnormal mitochondria. This gene is distinct from the gene encoding transcriptional coactivator with PDZ binding motif. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]