Mouse C8g activation kit by CRISPRa

CAT#: GA208161

C8g CRISPRa kit - CRISPR gene activation of mouse complement component 8, gamma polypeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: C8g
• Locus ID: 69379
• Kit Components:

  GA208161G1, C8g gRNA vector 1 in pCas-Guide-CRISPRa

  GA208161G2, C8g gRNA vector 2 in pCas-Guide-CRISPRa

  GA208161G3, C8g gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271777, NM_027062
• Summary: This gene encodes a secreted protein that is a core component of the complement 8 (C8) complex. C8 is part of the membrane attack complex which participates in the innate immune response against bacterial pathogens. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]