Mouse Acy3 activation kit by CRISPRa

CAT#: GA208886

Acy3 CRISPRa kit - CRISPR gene activation of mouse aspartoacylase (aminoacylase) 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Acy3
• Locus ID: 71670
• Kit Components:

  GA208886G1, Acy3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA208886G2, Acy3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA208886G3, Acy3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001302479, NM_001302480, NM_001302481, NM_001302482, NM_027857
• Synonyms: 0610006H10Rik; AA3; AAIII; Acy-3; AW107362; HCBP1
• Summary: This gene encodes a member of the aminoacylase family of enzymes. This enzyme specifically deacetylates N-acetyl aromatic amino acids and mercapturic acids. Action of this enzyme on metabolites of the environmental contaminant trichloroethylene leads to the generation of toxic products that may lead to kidney failure. This protein has been found to bind to the hepatitis C virus core protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]