Mouse Coasy activation kit by CRISPRa

CAT#: GA208921

Coasy CRISPRa kit - CRISPR gene activation of mouse Coenzyme A synthase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Coasy
• Locus ID: 71743
• Kit Components:

  GA208921G1, Coasy gRNA vector 1 in pCas-Guide-CRISPRa

  GA208921G2, Coasy gRNA vector 2 in pCas-Guide-CRISPRa

  GA208921G3, Coasy gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001305982, NM_027896
• Synonyms: 1300003G02Rik; Dpck; Ppat; Ukr1
• Summary: This gene encodes the bifunctional protein coenzyme A (CoA) synthase which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this protein catalyzes the conversion of phosphopantetheine into dephospho-CoA while its dephospho-CoA kinase domain completes the final step by phosphorylating dephospho-CoA to form CoA. [provided by RefSeq, Apr 2015]