Mouse Tysnd1 activation kit by CRISPRa

CAT#: GA208934

Tysnd1 CRISPRa kit - CRISPR gene activation of mouse trypsin domain containing 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Tysnd1
• Locus ID: 71767
• Kit Components:

  GA208934G1, Tysnd1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA208934G2, Tysnd1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA208934G3, Tysnd1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001272090, NM_001272091, NM_001272092, NM_027912, NR_073587
• Synonyms: 1300019N10Rik
• Summary: This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]