Mouse Dnmbp activation kit by CRISPRa

CAT#: GA209039

Dnmbp CRISPRa kit - CRISPR gene activation of mouse dynamin binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dnmbp
• Locus ID: 71972
• Kit Components:

  GA209039G1, Dnmbp gRNA vector 1 in pCas-Guide-CRISPRa

  GA209039G2, Dnmbp gRNA vector 2 in pCas-Guide-CRISPRa

  GA209039G3, Dnmbp gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001306088, NM_028029
• Synonyms: 2410003L07Rik; 2410003M15Rik; TUBA
• Summary: This gene encodes a member of the DBL family of guanine nucleotide exchange factors. The encoded protein has been proposed to regulate the actin cytoskeleton by specifically activating the Rho-family GTPase Cdc42. An interaction between the encoded protein and a Listeria protein has been shown to mediate Listeria infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]