Mouse Rptor activation kit by CRISPRa

CAT#: GA209854

Rptor CRISPRa kit - CRISPR gene activation of mouse regulatory associated protein of MTOR, complex 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Rptor
• Locus ID: 74370
• Kit Components:

  GA209854G1, Rptor gRNA vector 1 in pCas-Guide-CRISPRa

  GA209854G2, Rptor gRNA vector 2 in pCas-Guide-CRISPRa

  GA209854G3, Rptor gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001306081, NM_028898
• Synonyms: 4932417H02Rik; mKIAA1303; Rap; Raptor
• Summary: This gene encodes a subunit of mammalian target of rapamycin complex 1 (mTORC1), a component of the mTOR signaling pathway, which regulates cell growth in response to nutrient and energy levels. The encoded protein may regulate the assembly, localization, and substrate binding of the mTORC1 complex. Homozygous knockout mice for this gene exhibit embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]