Mouse Car12 activation kit by CRISPRa

CAT#: GA210515

Car12 CRISPRa kit - CRISPR gene activation of mouse carbonic anhydrase 12

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Car12
• Locus ID: 76459
• Kit Components:

  GA210515G1, Car12 gRNA vector 1 in pCas-Guide-CRISPRa

  GA210515G2, Car12 gRNA vector 2 in pCas-Guide-CRISPRa

  GA210515G3, Car12 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001306148, NM_178396
• Synonyms: 2310047E01Rik; AI314958; CA-XII; Ca12
• Summary: This gene encodes a membrane-bound member of the alpha carbonic anhydrase family of enzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate. These proteins participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]