Mouse Tnfrsf23 activation kit by CRISPRa

CAT#: GA211086

Tnfrsf23 CRISPRa kit - CRISPR gene activation of mouse tumor necrosis factor receptor superfamily, member 23

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Tnfrsf23
• Locus ID: 79201
• Kit Components:

  GA211086G1, Tnfrsf23 gRNA vector 1 in pCas-Guide-CRISPRa

  GA211086G2, Tnfrsf23 gRNA vector 2 in pCas-Guide-CRISPRa

  GA211086G3, Tnfrsf23 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001308111, NM_024290, NR_131763
• Synonyms: mDcTRAILR1; mSOB; SOB; Tnfrh1; Tnfrsf1al1; TNFRSFH23
• Summary: This gene encodes a member of the tumor necrosis factor superfamily of proteins. The encoded receptor has been shown to bind to the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), but to have no signaling capacity. This gene shows elevated expression in mice with diet-induced fatty liver disease. This gene and other family members are present in a gene cluster on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]