Mouse Bhlhe41 activation kit by CRISPRa

CAT#: GA211094

Bhlhe41 CRISPRa kit - CRISPR gene activation of mouse basic helix-loop-helix family, member e41

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Bhlhe41
• Locus ID: 79362
• Kit Components:

  GA211094G1, Bhlhe41 gRNA vector 1 in pCas-Guide-CRISPRa

  GA211094G2, Bhlhe41 gRNA vector 2 in pCas-Guide-CRISPRa

  GA211094G3, Bhlhe41 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271768, NM_024469
• Synonyms: 6430520M22Rik; Bhlhb2l; Bhlhb3; DEC2; Sharp1
• Summary: This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with Arntl or compete for E-box binding sites in the promoter of Per1 and repress Clock/Arntl's transactivation of Per1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2014]