Mouse Amn activation kit by CRISPRa

CAT#: GA211359

Amn CRISPRa kit - CRISPR gene activation of mouse amnionless

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Amn
• Locus ID: 93835
• Kit Components:

  GA211359G1, Amn gRNA vector 1 in pCas-Guide-CRISPRa

  GA211359G2, Amn gRNA vector 2 in pCas-Guide-CRISPRa

  GA211359G3, Amn gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_033603
• Synonyms: 5033428N14Rik; AV002116
• Summary: This gene encodes a type I transmembrane protein. The encoded protein is an essential component of the cubulin receptor complex which is thought to play a role in coordinating growth and patterning of the embryo. This protein is thought to modulate a bone morphogenetic protein (BMP) signaling pathway. A homoygous mutation in the mouse gene results in the lack of an amnion in embryos. Mutations in the human gene are associated with Megaloblastic Anemia-1. [provided by RefSeq, Sep 2015]