Mouse Ugt2a1 activation kit by CRISPRa

CAT#: GA211427

Ugt2a1 CRISPRa kit - CRISPR gene activation of mouse UDP glucuronosyltransferase 2 family, polypeptide A1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ugt2a1
• Locus ID: 94215
• Kit Components:

  GA211427G1, Ugt2a1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA211427G2, Ugt2a1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA211427G3, Ugt2a1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_053184
• Summary: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory epithelium. [UniProtKB/Swiss-Prot Function]