Mouse Wwtr1 activation kit by CRISPRa

CAT#: GA211463

Wwtr1 CRISPRa kit - CRISPR gene activation of mouse WW domain containing transcription regulator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Wwtr1
• Locus ID: 97064
• Kit Components:

  GA211463G1, Wwtr1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA211463G2, Wwtr1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA211463G3, Wwtr1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001168281, NM_133784
• Synonyms: 2310058J06Rik; 2610021I22Rik; C78399; Taz
• Summary: This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]