Mouse Gck activation kit by CRISPRa
CAT#: GA211775
Gck CRISPRa kit - CRISPR gene activation of mouse glucokinase
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Gck |
Locus ID | 103988 |
Kit Components | GA211775G1, Gck gRNA vector 1 in pCas-Guide-CRISPRa GA211775G2, Gck gRNA vector 2 in pCas-Guide-CRISPRa GA211775G3, Gck gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001287386, NM_010292 |
Synonyms | Gk; GLK; Gls006; HK4; HKIV; Hlb62; HXKP; MODY2 |
Summary | Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage. [UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN506364 | Gck - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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