Mouse Cpa1 activation kit by CRISPRa

CAT#: GA212247

Cpa1 CRISPRa kit - CRISPR gene activation of mouse carboxypeptidase A1, pancreatic

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cpa1
• Locus ID: 109697
• Kit Components:

  GA212247G1, Cpa1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA212247G2, Cpa1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA212247G3, Cpa1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025350
• Synonyms: 0910001L12Rik; Cpa
• Summary: This gene encodes carboxypeptidase A, a zinc-dependent metalloprotease that cleaves peptide bonds at the C-terminus of protein substrates. The encoded preproprotein undergoes proteolytic activation to generate a mature, functional enzyme. This gene is expressed in pancreas, the encoded protein is a major component of digestive enzymes secreted by pancreas and plays an important role in the process of digestion. This gene is located in a cluster of related carboxypeptidase genes on chromosome 6. [provided by RefSeq, Jan 2016]