Mouse Disp2 activation kit by CRISPRa

CAT#: GA213200

Disp2 CRISPRa kit - CRISPR gene activation of mouse dispatched RND tramsporter family member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Disp2
• Locus ID: 214240
• Kit Components:

  GA213200G1, Disp2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA213200G2, Disp2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA213200G3, Disp2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_170593
• Synonyms: AI840597; B230210L08Rik; DispB; mKIAA1742
• Summary: The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. [provided by RefSeq, Sep 2015]