Mouse Adamts2 activation kit by CRISPRa

CAT#: GA213371

Adamts2 CRISPRa kit - CRISPR gene activation of mouse a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Adamts2
• Locus ID: 216725
• Kit Components:

  GA213371G1, Adamts2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA213371G2, Adamts2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA213371G3, Adamts2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001277305, NM_175643
• Synonyms: ADAM-TS2; ADAMTS-2; ADAMTS-3; hPCPNI; mKIAA4060; PCINP; pNPI
• Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin repeats) family of proteinases that is involved in the proteolytic processing of procollagens. The encoded protein precursor is proteolytically processed to generate a mature, zinc-dependent enzyme. Mice lacking the encoded protein develop abnormal lungs, fragile skin and male sterility. [provided by RefSeq, Aug 2015]