Mouse Pomt2 activation kit by CRISPRa

CAT#: GA213500

Pomt2 CRISPRa kit - CRISPR gene activation of mouse protein-O-mannosyltransferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Pomt2
• Locus ID: 217734
• Kit Components:

  GA213500G1, Pomt2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA213500G2, Pomt2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA213500G3, Pomt2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_153415
• Synonyms: A830009D15Rik; AW046274
• Summary: This gene encodes an integral membrane protein that belongs to the dolichyl-phosphate-mannose-protein mannosyltransferase family. The encoded enzyme is found in the membrane of the endoplasmic reticulum. This protein is a component of the protein O-mannosyltransferase enzyme complex which is involved in modification of the protein alpha-dystroglycan. Mutations in the human gene are a cause of different forms of muscular dystrophy-dystroglycanopathy (MDDG), type A2 (also known as Walker-Warburg syndrome), type B2 and type C2 (also known as limb-girdle muscular dystrophy). [provided by RefSeq, Sep 2015]