Mouse Edc4 activation kit by CRISPRa

CAT#: GA214557

Edc4 CRISPRa kit - CRISPR gene activation of mouse enhancer of mRNA decapping 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Edc4
• Locus ID: 234699
• Kit Components:

  GA214557G1, Edc4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA214557G2, Edc4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA214557G3, Edc4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301100, NM_181594
• Synonyms: BC022641
• Summary: The protein encoded by this gene is thought to promote mRNA decay, and is known to interact with several mRNA decapping proteins. In humans, decreased expression of this gene prevents the accumulation of mRNA decapping proteins to mRNA processing bodies (P-body). Alternative splicing results in multiple protein isoforms. [provided by RefSeq, Jul 2014]