Mouse Adamts4 activation kit by CRISPRa
CAT#: GA214963
Adamts4 CRISPRa kit - CRISPR gene activation of mouse a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Adamts4 |
Locus ID | 240913 |
Kit Components | GA214963G1, Adamts4 gRNA vector 1 in pCas-Guide-CRISPRa GA214963G2, Adamts4 gRNA vector 2 in pCas-Guide-CRISPRa GA214963G3, Adamts4 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_172845 |
Synonyms | ADAM-TS4; ADAMTS-2; ADMP-1 |
Summary | This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active zinc-dependent aggrecanase enzyme that degrades cartilage. [provided by RefSeq, Jul 2016] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN500861 | Adamts4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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Product Citations
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