Mouse Nefh activation kit by CRISPRa

CAT#: GA217013

Nefh CRISPRa kit - CRISPR gene activation of mouse neurofilament, heavy polypeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Nefh
• Locus ID: 380684
• Kit Components:

  GA217013G1, Nefh gRNA vector 1 in pCas-Guide-CRISPRa

  GA217013G2, Nefh gRNA vector 2 in pCas-Guide-CRISPRa

  GA217013G3, Nefh gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010904
• Synonyms: mKIAA0845; NF-H; NF200; Nfh
• Summary: Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. [UniProtKB/Swiss-Prot Function]