COX2 (PTGS2) Human Gene Knockout Kit (CRISPR)
CAT#: KN202245RB
PTGS2 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | COX2 |
Locus ID | 5743 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000963 |
Synonyms | COX-2; COX2; GRIPGHS; hCox-2; PGG/HS; PGHS-2; PHS-2 |
Summary | 'Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]' |
Documents
Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN202245 | PTGS2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN202245BN | PTGS2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN202245LP | PTGS2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN402245 | PTGS2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA103907 | PTGS2 CRISPRa kit - CRISPR gene activation of human prostaglandin-endoperoxide synthase 2 |
USD 1,290.00 |
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