Mesothelin (MSLN) Human Gene Knockout Kit (CRISPR)
CAT#: KN202532RB
MSLN - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | MSLN |
Locus ID | 10232 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001177355, NM_005823, NM_013404 |
Synonyms | MPF; SMRP |
Summary | This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN202532 | MSLN - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN202532BN | MSLN - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN202532LP | MSLN - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN402532 | MSLN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA106960 | MSLN CRISPRa kit - CRISPR gene activation of human mesothelin |
USD 1,290.00 |
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