ERCC8 Human Gene Knockout Kit (CRISPR)
CAT#: KN203124
ERCC8 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | ERCC8 |
Locus ID | 1161 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000082, NM_001007233, NM_001007234, NM_001290285 |
Synonyms | CKN1; CSA; UVSS2 |
Summary | 'This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]' |
Documents
Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN203124BN | ERCC8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN203124LP | ERCC8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN203124RB | ERCC8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN403124 | ERCC8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA100833 | ERCC8 CRISPRa kit - CRISPR gene activation of human ERCC excision repair 8, CSA ubiquitin ligase complex subunit |
USD 1,290.00 |
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