PAK5 Human Gene Knockout Kit (CRISPR)
CAT#: KN205255
PAK5 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | PAK5 |
Locus ID | 57144 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_020341, NM_177990 |
Synonyms | PAK5 |
Summary | The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN205255BN | PAK7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN205255LP | PAK7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN205255RB | PAK7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN405255 | PAK5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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GA111404 | PAK5 CRISPRa kit - CRISPR gene activation of human p21 (RAC1) activated kinase 5 |
USD 1,290.00 |
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