APJ Receptor (APLNR) Human Gene Knockout Kit (CRISPR)
CAT#: KN207576RB
APLNR - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | APJ Receptor |
Locus ID | 187 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_005161, NR_027991 |
Synonyms | AGTRL1; APJ; APJR; HG11 |
Summary | 'This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN207576 | APLNR - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN207576BN | APLNR - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN207576LP | APLNR - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN407576 | APLNR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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GA100132 | APLNR CRISPRa kit - CRISPR gene activation of human apelin receptor |
USD 1,290.00 |
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