Aquaporin 7 (AQP7) Human Gene Knockout Kit (CRISPR)
CAT#: KN212363BN
AQP7 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | Aquaporin 7 |
Locus ID | 364 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001170, NM_001318156, NM_001318157, NM_001318158, NR_134513, NR_134514, NR_134515 |
Synonyms | AQP7L; AQP9; AQPap; GLYCQTL |
Summary | 'This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tubules of kidney, the encoded protein is localized to the apical membrane and prevents excretion of glycerol into urine. The encoded protein is present in spermatids, as well as in the testicular and epididymal spermatozoa suggesting an important role in late spermatogenesis. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related aquaporin gene on chromosome 9. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Dec 2015]' |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN212363 | AQP7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN212363LP | AQP7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN212363RB | AQP7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN412363 | AQP7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA100261 | AQP7 CRISPRa kit - CRISPR gene activation of human aquaporin 7 |
USD 1,290.00 |
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